Join Our Team!

**NEW POSTING**

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Endometriosis Oncogenomics and Pathology Research Lab (EDGE Research) at the University of British Columbia is seeking a highly motivated Postdoctoral Fellow to study the process driving malignant transformation of endometriosis to clear cell and/or endometrioid ovarian carcinomas. This work will form the basis of prevention, treatment, and etiological understanding of disease.

 

The successful candidate will work within a multidisciplinary team integrating molecular biology, genomics, epigenomics, microbiome science, proteomics, and clinical research. The position will focus on the development and evaluation of low-input whole genome sequencing and study of genotoxic stress markers. This project is funded through a four-year US Ovarian Cancer Research Program grant. This is an on-site position located at the UBC Vancouver Hospital Campus.

 

Key Responsibilities

• Project management and co-ordination of incoming specimen including maintaining ethics, operational approvals, and relationships with contributing hospitals.

• Support assay development and validation activities involving cellular and genotoxic stress, predominantly IHC/IF based assays.

• Lead review and enrichment (laser capture) of endometriosis, cancer, and control tissues for whole genome sequencing including co-ordination of external sequencing contracts and bioinformatics.

• Contribute to study design, data interpretation, quality control, and experimental troubleshooting.

• Lead genomic analysis and integration of multi-omics data including microbiome and cell stress phenotypes.

• Lead collaboration with spatial transcriptomics and functional genomics team (external). Assist with the development and optimization of laboratory and analytical workflows.

• Contribute to grant applications, manuscripts, reports, and presentations, with strong scientific writing skills and attention to reproducibility.

• Collaborate with clinicians, laboratory scientists, trainees, and external partners. This will include supervision, training and recruitment of junior trainees (e.g. undergraduate, and graduate students involved with aspects of the project)

 

Required Qualifications

• PhD in molecular biology, translational research, genomics, bioinformatics, proteomics, cancer biology, reproductive biology, or a related field. Experience in gynecologic cancer genomics is an asset.

• Experience with whole genome/whole exome next-generation sequencing analysis and related approaches is needed.

• Strong understanding of molecular pathology and biomarker development.

• Excellent organizational skills and attention to detail.

• Demonstrated ability to manage complex projects and work independently.

• Demonstrated commitment to research reproducibility and rigorous scientific practices.

• Excellent written communication skills, including experience assisting with grant writing, manuscripts, and scientific reports.

 

Preferred Qualifications

• Experience working with clinical specimens.

• Experience integrating multiple data types within translational research projects.

• Familiarity with women's health, reproductive biology, gynecologic cancers, and microbiome research.

• Experience collaborating across multidisciplinary teams.

• Flexible to travel to international conferences and collaborating sites in Canada, the US, and overseas.

• Eligibility for post-doctoral funding from MITACS (Elevate) and/or Canada Postdoctoral Research Award program (CPRA)

 

The ideal candidate is scientifically rigorous, highly organized, adaptable, and excited to work at the interface of molecular biology, translational medicine, and biomarker development.

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Salary range is commensurate to experience and is expected to be between $65-75,000pa plus benefits including extended health. Candidates with external funding will be eligible for incentive-award/top up funding.

 

This position will be cross posted via UBC [JR25408 Postdoctoral Research Fellow]

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To apply, provide a complete application package including:

1. A cover letter (2-page maximum) outlining your interest, potential to contribute, and qualifications/eligibility aligned to the advert above.

2. A full CV with publications/contributions to scientific advancement

3. Transcripts from most recent (terminal) degree.

4. Names and contact details for three professional references.

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Apply via UBC or send your application directly to the lab at apply@edgeresearch.ca (with OCRP Post-Doc in the subject line)

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 [incomplete applications will not be reviewed - please read the full posting]

 

Only qualified candidates will be contacted, and interviews will proceed on a rolling basis until the position is filled.

Do not reach out to lab members independently.

 

We invite applications from qualified candidates who share our commitment to employment equity and inclusive excellence, and we welcome applications from candidates belonging to historically, persistently, or systemically marginalized groups: Indigenous (First Nation, Métis, Inuit) Peoples, racialized persons, persons with disabilities, women, 2SLGBTQIA+ people, and trans and non-binary people.

 

EDGE Research hires on the basis of merit and is committed to employment equity. All qualified candidates are encouraged to apply; however, Canadians and permanent residents of Canada will be given priority.